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eCM XII: Implant
Infection
(Main focus orthopedic and trauma related infections)
22nd - 24th June, 2011, Congress Center, Davos, Switzerland
(Programme is subject to last minute changes)
Wednesday, June 22nd
| 08:30 – 08:40 |
R Geoff Richards AO Research Institute Davos |
| 08:40 – 08:50 |
Jaime Quintero President-elect AO Foundation |
| 08:50 – 09:00 |
Sibylle Grad Welcome to Davos |
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Musculoskeletal Infection
Session 1 Chair: Geoff Richards
| 09:00 – 09:30 |
Charlarampas Zalavras (USA)
Surgical treatment of infection in the presence of fracture fixation implants |
| 09:30 – 09:45 |
Sequential Release Kinetics of Two (Gentamicin and BMP-2) or Three (Gentamicin, IGF-1 and BMP-2) Substances from one-component Polymeric Coating on Implants
Britt Wildemann* |
| 09:45 –10:00 |
Daptomycin – Local Applications in Implant-Associated Infection and Complicated Osteomyelitis
Steffen Rosslenbroich* |
| 10:00 – 10:30 |
Henk Busscher (NL)
Biomaterials-related infection-the race for the surface and beyond |
10:30 – 11:00 Coffee Break
Anti-infective strategies I
Session 2 Chairs:Hans Griesser, Henk Busscher
| 11:00 – 1:30 |
Christof Berberich (DE)
Antibiotics in orthopedic use – is there a right choice? |
| 11:30 – 11:45 |
Ag/SiOxCy plasma polymer coating for antimicrobial protection of fracture fixation devices
V.Alt, P. Khalilpour, M. Wagener, E. Domann, R. Schnettler |
| 11:45 – 12:00 |
Controlled release of gentamicin for the prevention of Staphylococcus aureus biofilm formation on fracture fixation implants
R. Steck, D.J. McMillan, C. Lutton, N. Rosenzweig, K.S. Sriprakash, B. Goss,M.A. Schuetz |
| 12:00 – 12:30 |
Michael Raschke (DE)
Clinical performance of Antibiotic coated Intramedullary nails. |
Free afternoon
Bacterial Pathogenicity I
Session 3 Chairs:Mark Smeltzer, Fintan Moriarty
| 17:00 – 17:30 |
Sebastian Zaat (NL)
Peri-implant tissue as a “safe haven” for biofilm bacteria |
| 17:30 – 17:45 |
Influence of biomaterials on Staphylococcus epidermidis biofilm formation
L.G.Harris, R.Jeeves, H.Rohde, D.Mack |
| 17:45 – 18:00 |
Effects of rifampicin-fosfomycin coating for cementless endoprostheses against methicillin-sensitive S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA)
V.Alt, K. Lips, N. Düwelhenke, E. Domann, R. Schnettler |
| 18:00 – 18:30 |
Magnus Höök (USA)
S. aureus MSCRAMMS in Bone Infections |
18:30 – 20:00 Poster session (Drinks & Snacks)
Thursday, June 23rd
Anti-Infective strategies II
Session 4 Chairs: Michael Raschke, Llinos Harris
| 08:30 – 09:00 |
Klaus Dieter Kühn (DE)
Novel strategy of anti-infective implant coating in medicine |
| 09:00 – 09:15 |
Protecting polymer surfaces against bacterial adhesion and biofilm formation
Hans J. Griesser, Krasimir Vasilev, Hardi Ys, Chi Ndi, Stefani S. Griesser, Marek Jasieniak, Htwe Mon, Susan Semple |
| 09:15 – 09:30 |
Bone cell viability and antibacterial efficacy of porous TiO2-Ag coatings
B.S. Necula, L.E. Fratila Apachitei, J.P.T.M. van Leeuwen, S.A.J. Zaat, I. Apachitei, J. Duszczyk |
| 09:30 – 09:45 |
Antibacterial HA coatings with defined crystallinity to tune Ag release
S.Lischer, C.R. Bradbury, B.Wampfler, Q.Ren, Ph.Gruner, K.Maniura |
| 09:45 – 10:15 |
Noam Emanuel (IS)
PolyPid - A novel local delivery system: from the physic-chemical aspects to innovative and superior therapeutic potential. |
10:15 – 11:00 Coffee Break
Bacterial pathogenicity II
Session 5 Chairs: Mark Shirtliff, Charlarampas Zalavras
| 11:00 – 11:30 |
Mark Smeltzer (USA)
Alternative approaches for the diagnosis and treatment of staphylococcal biofilm-associated infection |
| 11:30 – 11:45 |
Serrulatane EN4, a New Antimicrobial Compound Exerts Potent Acitvity against Adherent Biofilm-Forming Bacteria In Vitro
J. Nowakowska, H. J. Griesser, C. Acikgoz, M. Textor, R. Landmann, N. Khanna |
| 11:45 – 12:00 |
Characterization of a three-species biofilm in vitro
M. Astasov-Frauenhoffer, O. Braissant, I. Hauser-Gerspach, A. U. Daniels, R. Weiger, T. Waltimo |
| 12:00 – 12:30 |
Dietrich Mack (UK)
Mechanisms of Staphylococcus epidermidis biofilm formation in different types of biomaterial-related infections |
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Free afternoon
Tour of AO center / Optional Hike in the vicinity of Davos
Immunological aspects of implant related infection
Session 6 Chairs: Sebastian A.J. Zaat, Dietrich Mack
| 17:00 – 17:30 |
Mark Shirtliff (USA) Novel vaccine strategies and improved diagnostics for musculoskeletal infections |
| 17:30 – 17:45 |
Development of a Passive Immunization for Methicillin-Resistant Staphylococcus aureus (MRSA) Osteomyelitis
SL. Kates, JJ. Varrone, JL. Daiss, EM. Schwarz |
| 17:45 – 18:00 |
In Vitro Modelling of Interactions between Bacteria, Osteoblast-like cells and Macrophages in the Pathogenesis of Biomaterial-Associated Infections
R. Kuijer, G. Subbiahdoss, I.C. Saldarriaga Fernández, J.F. da Silva Domingues, H.C. van der Mei, H.J. Busscher |
| 18:00 – 18:30 |
Jos A.G. van Strijp (NL)
Molecular mechanisms of complement evasion |
Free evening
Friday, June 24th
Asia Pacific Orthopaedic Association Session
Session 7 Chairs: Sureshan Sivananthan, John Fairclough
| 08:30 – 08:40 |
Sureshan Sivananthan
Introduction |
| 08:40 – 09:10 |
Said Saghieh (Lebanon)
Treatment of infected non-union of the long bones with calcium sulfate pellets impregnated with antibiotics |
| 09:10 – 09:40 |
John Fairclough (UK)
The surgical ritual – The myths and the science |
| 09:40 – 09:55 |
166 Cases of Mycobaterium Marinum Tenosynovitis of the Hand and Wrist: Clinical Features, Management and Results
Jason P Y Cheung* |
| 09:55 – 10:10 |
The Role of Occult Infection in the Aetiology of Aseptic Loosening Of Joint Arthroplasty Using Ultrasound Sonication and Conventional Sampling Techniques
J Kempthorne* |
| 10:10 – 10:20 |
APOA Session closing |
10:20 – 11:00 Coffee Break
Diagnosis and Imaging of infection
Session 8 Chairs: Stephen Kates, J.W. Costerton
| 11:00 – 11:30 |
Alberto Signore (Italy)
Radiolabelled leukocytes, antibodies and FDG for imaging infection associated to prostheses |
| 11:30 – 12:00 |
Vincent Stadlemann (CH)
Non-invasive biomechanical assessment of implant fixation with in-vivo computed tomography: perspectives for infected implants |
| 12:00 – 12:15 |
From swab to SEM: Our protocol on TKA infection suspicion
R.Ferrari, C.C.Castelli A.Goglio, A.Grigis, A. Raglio, S.Buoro, G.Virotta, A.Remuzzi, L.Condorelli |
| 12:15 – 12:30 |
Comparison of Cultures with a New Multiplex PC/Mass Spec. for the Detection of Orthopedic Biofilm Infections.
J.W. Costerton, N. Sotereanos and P.J. DeMeo |
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12:30 – 14:30 Lunch
Clinical focus
Session 9 Chairs: Niklaus Renner, Werner Zimmerli
| 14:30 – 15:00 |
IM Shapiro (USA)
Molecular Engineering of an Orthopaedic Implant: From Bench to Bedside |
| 15:00 – 15:10 |
Clinical Presentation and Bacteriological Analysis of Fight Bite Injuries in Tropical North Queensland
A.S. Miller, T. Ayres, P. Musio, J McBride, Wonnacott Dir |
| 15:10 – 15:20 |
Detection of periprosthetic joint infections: Blood infection markers in patients undergoing revision arthroplasty
T. Randau, M. Wimmer, D. Kuberra, B. Reichert, B. Stoffel-Wagner, D.-C. Wirtz, S. Gravius |
| 15:20 – 15:30 |
The use of Antimicrobial Peptides to prevent Implant Infections: Experimental Options and Review of Literature
S Sivananthan |
| 15:30 – 16:00 |
Werner Zimmerli (CH)
Antimicrobial treatment of implant-associated infections |
| 16:00 – 16:10 |
RMS Student prize announcements & Conference closing |
* Pfizer prize entrant
18:00 Conference Dinner including APOA Pfizer prize giving ceremony
Conference End
We advise all presenters to look at the TIPS
FOR TALKS (548 kB) presentation and read these guidelines
(39kB) before starting to prepare their talks. Science is in the
detail. It is the lifeblood of science to discuss.
All invited talks
are 20 minutes (20-30 slides)
to allow 10 minutes discussion per talk.
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5 minutes discussion per talk.
Chairpersons will cut people off who try to use this time for their
talks!
Please bring a copy of your talk on CD or USB stick to give to Presentation
Support, Wednesday morning at Registration.
Paper Submission
We invite all keynote speakers to submit a paper (either original
research report, original review*or original tutorial*) to the European
Cells & Materials (eCM) online 'Open & Free Access' journal.*NOTE:
We define a REVIEW PAPER as a paper which includes an extended literature
review and complete bibliography (including authors' own work),
and can also emphasise authors' new unpublished findings and in
an extended discussion puts the topic in proper perspective. A review
can also be based on a complete bibliography of an author's own
work over several years in relation to others. A TUTORIAL PAPER
contains an organised comprehensive review of all relevant published
material as for a teaching lecture.
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