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2012 eCM XIII: Bone Fixation, Repair & Regeneration
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| (Programme is subject to last minute changes) |  |
Sunday, June 24th
| 08:30 – 08:40 | R Geoff Richards AO Research Institute Davos |
| 08:40 – 08:50 | AO Foundation Video |
| 08:50 – 09:00 | Sophie Verrier Welcome to Davos |
Bone Diseases
Session 1 Chair: Jürg Gasser and Charlie Archer
| 09:00 – 09:30 | Jürg Gasser (Novartis, Switzerland) |
| 09:30 – 10:00 | Donald Salter (University of Edinburgh, Scotland, UK) |
| 10:00 –10:15 | The role of glutamatergic signalling in bone formation and arthritis |
10:15 – 11:00 Coffee Break
Bone Cell Biology
Session 2 Chair: Chris Evans
| 11:00 – 11:30 | Lynda Bonewald, (University of Missouri - Kansas City, USA) |
| 11:30 – 12:00 | Erik Fink Eriksen (Oslo University Hospital, Norway) |
| 12:00 – 12:15 | Wnt/β-catenin signalling pathway involved in the dual effects of desmethylicaritin on promotion of osteogenesis and inhibition of adipogenesis |
| 12:15 – 12:30 | In vitro 3D osteoblast-osteocyte co-culture model M Vazquez, BAJ Evans, JR Ralphs, D Riccardi, DJ Mason |
Free afternoon
Conference Social Walk (Optional)
Mechanical Regulation
Session 3 Chairs: Patrick Prendergast and Martin Stoddart
| 17:00 – 17:30 | Jenneke Klein Nulend (Academic Centre for Dentistry Amsterdam, Netherlands) The effect of mechanical loading on bone cells |
| 17:30 – 18:00 | Patrick Prendergast (Trinity Collage, Dublin, Ireland) |
| 18:00 – 18:15 | Alveolar bone resorption is triggered by sudden strain relaxation of gingival fibroblasts |
18:15 – 20:00 Poster session (Drinks & Snacks)
Monday, June 25th
Polymers for Bone repair and regeneration
Session 4 Chairs: Marc Bohner and David Eglin
| 08:30 – 09:00 | Dirk Grijpma (University of Twente, Netherlands) Composite biomaterials for bone repair and regeneration -reconstruction of orbital floor defects in an animal model |
| 09:00 – 09:15 | Resorption characteristics of Chronos™ inject in metaphyseal bone defects caused by distal radius fracture CM Sprecher, R Arora, M Lutz, I Sitte, S Duda, M Blauth, S Milz |
| 09:15 – 09:45 | Marc Bohner (RMS Foundation, Switzerland) |
| 09:45 – 10:00 | An injectable in situ forming composite gel to guide bone regeneration: design and development of technology platform |
| 10:00 –10:15 | Low modulus novel bone substitutes for osteoporotic vertebral fracture management |
| 10:15 – 10:30 | Type I collagen coating improves implant osteointegration in vivo S Cecconi, M Mattioli-Belmonte, S Manzotti, A Gigante |
| 10:30 – 10:45 | Bioactive PLGA/TCP/Icaritin composite scaffolds reduce incidence of joint collapse in steroid-associated osteonecrotic femoral head of bipedal emus |
| 10:45 – 11:00 | Biogenic hydroxyapatite from eggshell as bone formation material |
11:00 – 11:30 Coffee Break
Vascularisation
Session 5 Chairs: Joelle Amedee and Sophie Verrier
| 11:30 – 12:00 | Matthias Laschke (University of Saarland, Germany) Angiogenesis and inosculation in bone tissue engineering |
| 12:00 – 12:30 | Joelle Amedee (Université Bordeaux Segalen, France) |
| 12:30 – 12:45 | Co-seeding of EPC/MSC in 3D scaffolds (Endothelial Progenitor Cells / Mesenchymal Stem Cells) promotes implant's neovascularization: evidence of pericytes' participation. |
Free afternoon
18:00 Conference Dinner
Tuesday, June 26th
Bone Tissue Engineering
Session 6 Chairs: Thimios Mitsiadis and Joost de Bruijn
| 08:30 – 09:00 | Ivan Martin (University Hospital Basel, Switzerland) |
| 09:00 – 09:30 | Gianpaolo Papaccio (Second University of Naples, Italy) |
| 09:30 – 09:45 | Developmental engineering of a bone organ with human adult mesenchymal stem cells |
| 09:45 – 10:00 | A comparison of endochondral ossification by vessel derived stem cells and mesenchymal stem cells in wild type and ApoE-/- mice A Leszczynska, E Farrell, A O’Doherty, F O’Brien, T O’Brien, M Murphy |
| 10:00 – 10:15 | Bone formation using autologous bone marrow derived mononuclear cells combined with β-tricalcium phosphate (β-TCP) and absorbable atelocollagen for the treatment of aneurysmal bone cyst of the humerus in child |
| 10:15 – 10:30 | Pig as large animal model for cell therapy in bone tissue engineering |
10:30 – 11:00 Coffee Break
Biological Modifiers
Session 7 Chair: Mauro Alini
| 11:00 – 11:30 | Kurt Hankenson (University of Pennsylvania, USA) |
| 11:30 – 12:00 | Stephen Badylak (McGowan Institute for Regenerative Medicine, Pittsburgh, USA) |
| 12:00 – 12:15 | IL-1β modulates in vitro remodeling and in vivo bone formation by endochondral primed human bone marrow mesenchymal stromal cells |
12:15 – 14:30 Lunch
Clinical Perspectives (Sponsored by AOTrauma)
Session 8 Chair: Geoff Richards
| 14:30 – 15:00 | Frankie Leung ( University of Hong Kong, Queen Mary Hospital, Hong Kong) |
| 15:00 – 15:30 | Paul Heini (Klinik Sonnenhof, Bern, Switzerland) |
| 15:30 - 16:00 | Risto Kontio (Finland) Jaw bone reconstruction using CAD and stem cell technology |
| 16:00– 16:30 | John Fairclough (Cardiff and Vale Orthopaedic Centre, Wales, UK) |
| 16:30 – 17:00 | Robert Mathys Student prize announcements & Conference closing |
| 17:00 – 17:15 | Official photograph of attendees |
Conference End
We advise all presenters to look at the TIPS
FOR TALKS (548 kB) presentation and read these guidelines
(39kB) before starting to prepare their talks. Science is in the
detail. It is the lifeblood of science to discuss.
All invited talks
are 20 minutes (20-30 slides)
to allow 10 minutes discussion per talk.
All submitted talks are 10 minutes (10-15 slides) to allow
5 minutes discussion per talk.
Chairpersons will cut people off who try to use this time for their
talks!
Please bring a copy of your talk on CD or USB stick to give to Presentation
Support, Wednesday morning at Registration.
Paper Submission
We invite all keynote speakers to submit a paper (either original
research report, original review*or original tutorial*) to the European
Cells & Materials (eCM) online 'Open & Free Access' journal.*NOTE:
We define a REVIEW PAPER as a paper which includes an extended literature
review and complete bibliography (including authors' own work),
and can also emphasise authors' new unpublished findings and in
an extended discussion puts the topic in proper perspective. A review
can also be based on a complete bibliography of an author's own
work over several years in relation to others. A TUTORIAL PAPER
contains an organised comprehensive review of all relevant published
material as for a teaching lecture.
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