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Volume No 10 - Supplement 3 - July
2005
Abstracts of European Cells and Materials VI /SRN I
Spinal Motion Segment: From Basic Science to Clinical Application
4th - 7th July 2005, Congress Centre, Davos, Switzerland
Abstracts listed in order of presentation at the meeting
Page
1 : C Schizas
Spinal fusion: techniques results and limitations
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2 : R Gunzburg, P Willocx
Disc arthroplasty, surgical approaches
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3 : M Ahrens, JC Le Huec, H Halm, U Liljenqvist, J Sherman,
T Schulte, E Martz, S Hook, H Yuan
A new procedure for total nucleus removal from the posterior approach
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4 : HJ Meisel, A Beier, T Hoell, Y Minkus, T Ganey, WC Hutton
Transient reduced mineral density associated with BMP-enhanced spinal
fusion
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5 : C Tournier, JC Le Huec, S Aunoble, JP Lemaire, P Tropiano,W
Skalli
Total disc arthroplasty: consequences for sagittal balance and lumbar
spine movement
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6 : M Morra, C Cassinelli, G Giavaresi, M Fini, R Giardino
Enhanced osteointegration by biochemical surface modification: covalent
linking of collagen I to intervertebral metal disk surface
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7 : M Aebi
The myths and the facts of disc arthroplasty surgery
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8 : KDK Luk, DK Ruan, DS Lu, DHK Chow, KMC Cheung
Allogeneic intervertebral disc transplantation: Results of pre-clinical
and clinical studies
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9 : DO Halloran, M White, R Collighan, M Griffin, A Pandit
Scaffold characterisation for nucleus pulposus regeneration
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10 : E Boelen, C van Hooy-Corstjens, A van Ooij, L van Rhijn,
L Koole
Preclinical evaluation of intrinsically radiopaque hydrogels for
replacing the nucleus pulposus
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11 : F Heuer, L Claes, H-J Wilke
Can the biomechanical disc function be restored by a collagen matrix
nucleus replacement
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12 : S Olsen, Á Higgins Ní Chinnéide, W-R
Fritz, SJ Ferguson
Re-swelling degenerate intervertebral discs by percutaneous injection:
an in-vitro investigation
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13 : GBJ Andersson
Is the Disc a Source of Back Pain?
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14 : JR Ralphs
Cell-cell interactions and the cytoskeleton in organisation of the
developing intervertebral disc
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15 : CJ Hunter
The notochordal cell in the postnatal intervertebral disc
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16 : J Chen, W Yan, IA Setton
Molecular phenotypes of notochordal cells purified from nucleus
pulposus via fluorescence-activated cell sorting
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17 : PJ Roughley, L Melching, JS Mort, RH Pearce, S Sivan, A
Maroudas
The structure, degradation and lifespan of aggrecan in the human
intervertebral disc
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18 : MA Adams
Mechanical influences in disc degeneration
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19 : JC Iatridis
Effects of mechanical loading on disc metabolism
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20 : E Kelly, NA Duncan
Intercellular communication via gap junctions in the annulus
fibrosus
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21 : C Neidlinger-Wilke, K Würtz, W Börm, A Ignatius,
H-J Wilke, L Claes
Regulation of gene expression in intervertebral disc cells by low
and high hydrostatic pressure
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22 : LA Setton
Cell mechanics and mechanobiology in the intervertebral disc
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23 : T Oegema
The role of extracellular matrix and matrix molecular fragments
in disc degeneration
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24 : S Roberts, J Menage, EH Evans, SM Eisenstein
Proteinases in degeneration of the intervertebral disc: cause and
effect
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25 : M Haefeli, F Kalberer, D Saegesser, AG Nerlich, N Boos,
G Paesold
The course of macroscopic degeneration in the human lumbar intervertebral
disc
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26 : H Bertram, E Steck, G Zimmermann, B Chen, C Carstens, A
Nerlich, W Richter
Accelerated intervertebral disc degeneration in scoliosis versus
physiological ageing develops against a background of enhanced anabolic
gene expression
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27 : JPG Urban, O Boubriak, T Grunhagen, SR Smith, JCT Fairbank,
D Mokhbi Soukane, A Shirazi-Adl.
Factors influencing nutrition of the intervertebral disc
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28 : KMC Cheung, JJT Jim, J Ott, J Karppinen, KDK Luk, S-P Yip,
PC Sham, Y-Q Song, JCY Leong, KSE Cheah, L Ala-Kokko, D Chan
The genetics of intervertebral disc degeneration
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29 : MC Battié
Determinants of disc degeneration and pathology: A major paradigm
shift
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30 : S Majumdar, G Blumenkrantz, K Keshari ,T Link
Recent advances in MRI markers of disc degeneration
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31 : W Johannessen, JD Auerbach, AJ Wheaton, A Kurji, R Reddy,
A Borthakur, DM Elliott
Non-invasive determination of nucleus pulposus proteoglycan content
using T1 MRI
*** won the Hansjoerg Wyss Foundation Oral Presentation Award
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32 : S Rehman, S Johnson, K McKinlay, NM Everitt, DS McNally
Micro observations the intervertebral disc
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33 : H Wang, R Glauben, K Gebhard, M Buchner, M Schiltenwolf,
E Raum, H Brenner, B Mueller-Hilke, W Richter
High serum level of TNF-alpha correlates with chronic low back pain
but not acute sciatica
Page
34 : AS Turner
Spine surgery in a large animal model: Experiences and limitations
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35 : J Melrose, M Smith, S Smith, A Young, S-Y Hwa, C Smith,
A Dart, CB Little
Investigations using an ovine annular lesion model of experimental
intervertebral disc degeneration
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36 : B Jim, O Arlet, L Beckman, T Steffen
The influence of harvesting methods for the development of an in-vitro
intervertebral disc model
****Robert Mathys Foundation award winner for the best student oral
presentation
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37 : B Gantenbein, CR Lee, M Alini, K Ito
An in vitro tissue culture system for ovine caudal intervertebral
discs with endplates
Page
38 : K Masuda, H An
Biological repair and a preventive approach for disc degeneration
Page
39 : H-J Meisel, O Alasevic, W Hutton, T Ganey
Disc repair with autologous chondrocytes: A pilot clinical study
Page
40 : ST Yoon
Molecular therapy of intervertebral disc
Page
41 : LG Gilbertson, PD Robbins, JD Kang
BMP-2 gene transfer alters course of disc degeneration in rabbit
model
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42 : R Kandel, C Seguin, D Hamilton, M Grynpas, R Pilliar, M
Hurtig
Towards bioengineering a scaffold-free nucleus pulposus
Page
43 : D Sakai, J Mochida
Stem cell applications in cell therapy for nucleus repair
Page
44 : WEB Johnson, A Wootton, A El Haj, SM Eisenstein, ASG Curtis,
S Roberts
Topographical guidance of intervertebral disc cell growth in
vitro: Towards the development of tissue repair strategies for
the annulus fibrosus
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45 : KMC Cheung, G Ho, VYL Leung, D Chan
The effect of severity of disc degeneration on mesenchymal stem
cells' ability to regenerate the intervertebral disc: a rabbit model
Posters
Page
46 : M Ahrens, N Ordway, A Tsantrizos, H Yuan, B Bowman
Nucleus replacement with an in situ curable balloon contained
polymer and restoration of segmental kinematics
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47 : J Antoniou, F Mwale, CN Demers, G Beaudoin, T Goswami,
L Beckman, M Alini
MRI and biochemical properties in dynamic loading studies of bovine
intervertebral discs: Effect of loading conditions
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48 : M Attawia, T Chujo, K Akeda, HS An, E Thonar, K Masuda
In vivo effects of recombinant human growth and differentiation
factor 5 on the intervertebral disc
Page
49 : H Beard, CG Schultz, MR Zarrinkalam, RJ Moore
Further characterisation of an ovine model of steroid-induced osteopaenia
Page
50 : L Beckman, K Debiparshad, D Giannitsios, N Boos, T Steffen
Low stiffness biopolymer used for mechanical bone augmentation in
osteoporotic vertebrae
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51 : S Boden, J-L Ugbo, C Oliver, A Briest
Osseogenetic collagen complex as an effective graft alternative
in experimental posterolateral lumbar spine arthrodesis
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52 : KMC Cheung, G Ho, D Chan, VYL Leung
Regeneration of nucleus pulposus after discectomy by autologous
mesenchymal stem cells: a rabbit model
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53 : AK Darwesh, WW Lu, KMC Cheung, KWK Yeung, D Chan
Impact of Trp2 allele mutation of alpha-2 chain in collagen IX on
the structural integrity of human annulus fibrosus
Page
54 : D Giannitsios, S Ferguson, P Heini, G Baroud, T Steffen
High cement viscosity reduces leakage risk in vertebroplasty
Page
55 : D Giannitsios, C Richards, J Ouellet, P Jarzem, T Steffen
Comparison of pedicle screw spinal fixation for fractures: Bridge
vs. tension band construct
Page
56 : CXX Guo, MG Irwin, D Chan, GL Tipoe, KMC Cheung
Differential functions of cyclooxygenase 1 and 2 in bone repair
Page
57 : D Haschtmann, J Stoyanov, L Ettinger, L-P Nolte, SJ Ferguson
Establishment of an in-vitro whole organ intervertebral disc
/ endplate culture model
Page
58 : RJW Hoogendoorn, MN Helder, TH Smit, PIJM Wuisman
Slowly progressive disc degeneration in a goat model
Page
59 : RJW Hoogendoorn, MN Helder, TH Smit, PIJM Wuisman
Notochordal cells in mature caprine intervertebral discs
Page
60 : M Huttunen, M Kellomäki, P Törmälä,
N Ashammakhi
Bioresorbable fibre reinforced composites for spinal fusion application:
In vitro analysis
Page
61 : B Jim, T Steffen
Potential nuclear replacement materials: Developing a screening
process
Page
62 : JC Iatridis, JJ MacLean, JP Owen
Role of endplates in contributing to compression behaviors of motion
segments and intervertebral discs
*** won the Hansjoerg Wyss Foundation poster Presentation Award
Page
63 : A Lai, DHK. Chow, WS Siu, AD Holmes, MCP Leung, FH Tang
The biomechanical effects of electrical stimulation on degenerative-like
changes intervertebral disc
Page
64 : H Li, X Zou, C Woo, M Ding, M Lind, C Bünger
Lumbar spine fusion with a novel tantalum-coated carbon fibre cage
loaded with Colloss®
Page
65 : L Mejia, J Lusk, T Nickel
Design considerations for a multi-DOF kinematic spine simulator
Page
66 : A Reiband, B Mrozik, G Hoffmann, P Offermann, G Schmack,
W Pompe, M Gelinsky
Scaffolds for intervertebral disc tissue engineering created by
flock technology
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67 : A Rohlmann, T Zander, G Bergmann
Influence of cement augmentation on intradiscal pressure: A finite
element study
Page
68 : A Rohlmann, T Zander, H Schmidt, H-J Wilke, G Bergmann
Effect of disc degeneration on the mechanical behavior of a lumbar
functional spinal unit
Page
69 : I Sitte, A Kathrein, M Klosterhuber, GP Dowthwaite, C Archer
Notch 1 expression as a sign for proliferation in Anulus Fibrosus
after trauma of the cervical spine? An histological, immunhistological
and ultrastructural study
Page
70 : CM Sprecher, J Goldhahn, E Schneider
Short term observations on Bonit coated surfaces in self cutting
implants
Page
71 : Y Schroeder, D McNally, K McKinlay, W Wilson, JM Huyghe,
FPT Baaijens
Comparison of experimental and numerical stress profiles in human
disc show similar stress peaks why?
****Robert Mathys Foundation award winner for the best student poster
presentation
Page
72 : M Schuler, TP Künzler, CM Sprecher, M de Wild, S Tosatti,
M Textor
TiO2-coated epoxy replicas with identical surface topography for
cell culture experiments
Page
73 : MA Tyndyk, V Barron, PE McHugh
Effect of osteoporosis on the biomechanics of the thoracolumbar
spine: Finite element study
Page
74 : AJ van der Veen, MG Mullender, MN Helder, PIJM Wuisman,
ThH Smit
Mechanical behavior of iv discs stabilizes in a loaded culture system
Page
75 : MJ van der Werf, P Lezuo, O Maissen, K Ito
An in vivo nutrient insufficiency induced ovine lumbar intervertebral
disc degeneration model
Page
76 : H Wang, HM Byrne, DS McNally
Mathematical modeling of the intervertebral disc nutritional transport
Page
77 : K Würtz, JPG Urban, A Ignatius, H-J Wilke, L Claes,
C Neidlinger-Wilke
Cells from the distinct regions of the intervertebral disc differ
in terms of their mechanosensitivity
Page
78 : KWK Yeung, RWY Poon, X Liu, JPY Ho, CY Chung, PK Chu, WW
Lu, D Chan, KMC Cheung
Nickel suppression in Ni-Ti alloys by plasma immersion ion implantation
surface treatment: new materials for orthopaedic implantation
Page
79 : S Zeiter, CR Lee, M Alini, K Ito
Effect of TGF-beta and BMP-2 on rat mesenchymal stem cell differentiation
into disc-like cells in vitro
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