Volume No 12 - Supplement 1- August
2006
Abstracts of European Cells and Materials VII
Cartilage and Joint Repair
June 26th - 29th 2006, Congress Centre, Davos, Switzerland
Abstracts listed in order of presentation at the meeting
Cartilage Development
Page
1 : C Hartmann
Importance of Wnt-signaling during embryonic skeletogenesis
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2 : CW Archer
The isolation and partial characterisation of progenitor cells from
foetal and aged human articular cartilage
Page
3 : E Lundgren-Ackerlund, L Varas, A-K Lindqvist, C Kjellman
Integrin alpa10beta1, a unique cell-surface for chondrogenic cells
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4 : LC Hughes, C Archer, I ap Gwynn
Stages of murine articular cartilage development
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5 : A Vortkamp
Indian hedgehog signalling in the embryonic growth plate
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6 : H Agoston, S Khan, C James, F Beier
C-Type natriuretic peptide regulates endochondral bone growth in
a P38 map kinase-dependent manner (Joint Winner of the Prize
for the best presentation)
Page
7 : V Ulici, F Beier
The PI3K/Akt pathway regulates endochondral bone growth
Page
8 : L Sandell
Lack of Endochondral Ossification in Site-1 Protease Knockout Mice
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9 : E Steck, AN Maurer, H Kalbacher, W Richter
Chondrocyte secreted CRTAC1: an extracellular matrix molecule of
human articular cartilage facilitates cell adhesion
Cartilage Biochemistry
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10 : D Heinegard
Cartilage eCM molecules with roles in tissue homeostasis
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11: P Roughley
The function of cartilage proteoglycans
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12: CTG Appleton, DD McErlain, V Pitelka, JL Henry, D Holdsworth,
F Beier
Chondrocyte gene expression in a rat model of osteoarthritis
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13: S Chubinskaya, L Otten, S Soeder, R Loeser, T Aigner, DC
Rueger
Role of osteogenic protein-1 in the regulation of catabolic and
anabolic pathways
Page
14: D Eyre
Articular cartilage collagen - an irreplaceable framework?
Cartilage Biomechanics
Page
15: Robert Sah
A model of synovial fluid lubricant composition in normal and inflamed
joints
Page
16: Y Takahashi, K Yamamoto, S Chueh, Y Tamada, N Tomita
Effects of relative sliding stimulus on the friction properties
of regenerated cartilage
Page
17: ARC Jones, C Keohan, R Sheldon, M Majumdar, EA Morris, R
Zollner, CR Flannery
Regulation of lubricin expression and metabolism in synovial joints
Page
18: G Ateshian
Finite element analysis of strain fields in chondrocytes and the
extracellular matrix of cartilage under physiological loading
Page
19: U-J Goerke, MA Wimmer, M Alini, E Schneider, H Guenther
Multiscale finite element modelling in tissue engineering of articular
cartilage
Page
20 : M Wimmer
Mechanical and cellular response of impaction cycles on osteochondral
grafts
Cartilage Degradation
Page
21: J Mort
Proteases in cartilage degradation
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22: B Fermor
Oxygen, Nitric Oxide, and Osteoarthritis
Page
23: CM Davies, F Guilak, JB Weinberg, B Fermor
Inerleukin-1 induction of DNA damage in articular cartilage: roles
of nitric oxide and superoxide
Page
24: A Fosang
Is ADAMTS-5 the only aggrecanase in mouse cartilage?
Page
25: T Aigner
IL-1ß and BMP-7 - Interactive players of catilage matrix degradation
and regeneration
Cartilage repair: Present
Page
26: R Jakob
AMIC technique for cartilage repair, a single-step surgical intervention
as compared to other methods
Page
27: J Richardson
Is ACI a success? Current evidence and trials in progress
Page
28: S Majumdar
MR Imaging and Early Cartilage Degeneration Detection
Page
29: S Grohmann, R Schade, J Martini, D Anselmetti, K Liefeith
Visualization of chondrocytes on collagen scaffolds by two photon
laser scanning microscopy (TPLSM) (Joint Winner of the Prize
for the best presentation)
Page
30 : J Jurvelin
Biophysical diagnostics of normal, degenerated and repaired articular
cartilage
Page
31: S Laverty
The pros and cons of studies of animal joints to improve articular
cartilage regeneration
Cartilage repair: Future
Page
32: F Barry
Stem cell strategies for cartilage repair
Page
33: T Hennig, H Lorenz, K Goetzke, C Lee, W Richter
A comparison of the different growth factor repertoire and the factor
requirement for successful chondrogenesis of MSC's from bone marrow
and adipose tissue
Page
34: F Mwale, P-L Girard-Lauriault, HT Wang, S Lerouge, J Antoniou,
MR Wertheimer
Suppression of hypertrophy and osteogenesis in committed human mesenchymal
stem cells cultured on novel nitrogen-rich plasma polymer coatings
Page
35: B Johnstone
Skeletal tissue regeneration with stem cells
Page
36: H Lorenz, T Hennig, W Richter
Chondrogenic differentiation in adipose tissue derived mesenchymal
stem cells: Effects of growth factors and PTHrP
Page
37: A Crawford, DJ Kelly, SC Dickinson, TJ Sims, J Mundy, AP
Hollander, PJ Prendergast, PV Hatton
Biochemical markers of the mechanical quality of engineered hyaline
cartilage
Page
38: C De Bari
Cell-based approaches to joint surface repair: from bench to bedside
Page
39: M Sato
Cell sheet technology for cartilage repair
Page
40 : R Takaya, N Kachi, N Tomita
Micro-folding culture: A new method of making multicellular aggregate
Page
41: Ivan Martin
Bioreactors for cartilage tissue engineering
Page
42: C Vinatier, O Gauthier, M Masson, D Magne, C Merceron, A
Moreau, F Moreau, P Weiss, J Guicheux
Transplantation of nasal chondrocytes with an innovative self-setting
hydrogel for cartilage repair
Page
43: C Vinatier, O Gauthier, M Masson, O Malard, A Moreau, F
Moreau, B Bilban, R Spaethe, A Goppelt, G Daculsi, P Weiss, J Guicheux
Nasal chondrocytes and fibrin sealant for cartilage tissue engineering
Page
44: C Evans
Molecular approaches to cartilage repair
Page
45: T Schmid
PRG4/lubricin/SZP and the slippery side of cartilage
Page
46: M Alini
Articular motion induces SZP in chondrocytes-seeded 3-D scaffolds:
Link between joint motion and joint lubrication?
Page
47: LJ Bonassar
Frictional Properties of Engineered Cartilaginous Tissues in Boundary
Lubrication
Page
48: GD Jay
Friction Reducing Properties of Lubricin (Prg4): A Nanoscale Study
of Chondroprotection
Page
49: C Flannery
Therapeutic perspectives for lubricin and joint function
Posters
Page
50 : C Adamczyk, T Tischer, R Putz, M Benjamin, S Milz
The adaptation of human pisiform entheses to compressive forces
Page
51: W Anderl, P Heuberger, B Kriegleder, M Neumaier, H Plenk
Jr.
Adverse cell and tissue reactions during delayed degradation of
PLDLA-anchors for shoulder joint repair
Page
52: C Curtin, B Curtin, M Murphy, F Barry
Stem cell delivery of osteoarthritic tissue
Page
53: EJ Blain, VC Duance
Maintenance of chondrocyte phenotype by the vimentin intermediate
filaments
Page
54: L Davies, E Blain, B Caterson, V Duance
Comparing the responsiveness of chondrocytes isolated from young
and mature articular cartilage to IGF-1 and TGFbeta1
Page
55: GP Dowthwaite, SN Redman, LM Haughton, JA Fairclough, AS
Williams, CW Archer
Identification of human chondroprogenitor cell populations
Page
56: C Forkmann, M Alini, U-J Görke, MA Wimmer, H Günther
Identification of hyperelastic parameters of porous polyurethane
sponges
Page
57: K Gelse, J Park, K von der Mark, T Aigner, F Henning, H
Schneider
BMP-2 transgene-stimulated adult mesenchymal cells for articular
cartilage repair (Joint Winner of the Prize for the best
poster)
Page
58: LM Haughton, GP Dowthwaite, SN Redman, AS Williams, CW Archer
Spatial pattern of the delta-notch signalling pathway on osteoarthritic
cartilage
Page
59: F Hildner, M van Griensven, G Schüller, A Peterbauer,
C Gabriel, H Redl
Ability of BMP-6 and FGF-2 to induce chondrogenic differentiation
in adipose-derived stem cells
Page
60 : LC Hughes, C Archer, I ap Gwynn
The development and structural integrity of articular cartilage
in collagen IX decorin and matrilin-1 knockout mice (Joint
Winner of the Prize for the best poster)
Page
61: RW Kang, AH Gomoll, JM Williams, BR Bach, BJ Cole
Chondrolysis after continuous intra-articular bupivacaine infusion.
An experimental model investigation chondrotoxicity in the rabbit
shoulder
Page
62: RW Kang, PC McCulloch, MH Sobhy, JK Hayden, BJ Cole
Prospective evaluation of prolonged fresh osteochondral allograft
transplantation of the femoral condyle: Minimum 2 year follow-up
Page
63: IM Khan, CW Archer
Oxidative stress induces expression of markers of early osteoarthritis
and chondrocyte terminal differentiation in cultured bovine explants
Page
64: P Marcus, C De Bari, F Dell'Accio, G Dowthwaite, CW Archer
The in vivo fate of implanted chondroprogenitor cells in
SCID mice
Page
65: S Nürnberger, F Wiesauer, S Marlovits
Two year long-term study of human MACT-grafts in vitro
Page
66: CO Flatharta, W Curtin, FP Barry, G Henihan, JM Murphy
Mesenchymal stem cell senescence in osteoarthritis
Page
67: E Pirhonen, L Moimas, P Väänänen
Porous bioactive glass scaffold with high compression strength
Page
68: I Ponomarev, D Paul, M Neumann, I Wilke
Scaffold-free chondrocyte transplantation as alternative to matrix
associated chondrocyte transplantation
Page
69: SN Redmann, N Bateman, LM Haughton, GP Dowthwaite, AS Williams,
CW Archer
Evidence of a chondroprogenitor population in human osteoarthritic
cartilage
Page
70 : K Richardson, IM Khan, CW Archer
Identifying progenitor cells within articular cartilage
Page
71: K Saldanha, J Lozano, CB Ma, HT Kim, S Majumdar
MRI of iron oxide labelled stem cells: Application to tissue regeneration
Page
72: M Stoddart, L Ettinger, HJ Häuselmann
Effect of mechnical load on matrix synthesis in scaffold free, de
novo cartilage - like tissue
Page
73: RS Tigli, M Gümüsderelioglu
Dexamethasone releasing chitosan scaffold for cartilage development
Page
74: R Williams, GP Dowthwaite, DJ Evans, C Archer
Notch family signalling and notch signalling modulation during chondrogenesis
Page
75: S Williams, T Banse, W Conrads, T Nickel, L Mejja
BioDynamic test instrument for Characterization of tissue and biomaterials
Page
76: M Wimmer, TK Pylawka, JM Williams, M Honl
Water-Jet cutting of articular cartilage to improve cell viability
in cartilage repair
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