Volume No 13 - Supplement 2 - 2007
Biotechnology Symposium
From basic research to clinical applications using biotechnology
and bioengineering. Lausanne, Switzerland, October 19 to 21, 2006
Abstracts listed in order of presentation at the meeting
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1 : Margarethe Hofmann-Amtenbrink
Biotechnology in the AO Foundation
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2 : James Kellam
The AO Foundation: ready for the future?!
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3 : Norbert Suedkamp
Clinical needs and applications of mesenchymal stem cells
Tissue Engineering and Bone Healing
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4 : Norbert Haas
Biotechnology in trauma
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5 : Tom Oxland
Strategies to reconstitute the proximal femur after failed total
hip replacement
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6 : Esmaiel Jabbari
In-situ crosslinkable osteoinductive poly(lactide) scaffold
for bone regeneration
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7 : Carl Haasper
Compression enhances cell distribution and scaffold stability of
osteochondral matrix constructs
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8 : Karen Burg
Tissue-engineered bone replacement systems
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9 : Robert Guldberg
Strategies for segmental bone repair
Tissue Engineering and Cartilage Regeneration
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10 : Rita Kandel
Biphasic constructs for cartilage repair
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11: Henning Madry
Gene therapy for the regeneration of traumatic articular cartilage
defects
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12: Mark A Randolph
Photo-crosslinking collagen gel for tissue engineered cartilage
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13: Markus A Wimmer
Numerical simulation of functional tissue engineering for articular
cartilage
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14: Charles Archer
Cartilage repair using a specific articular progenitor cell
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15: Brigitte von Rechenberg
Silk as an adaptable 3-D matrix for defect repair in subchondral
and cranial bone
Tissue and Bio-engineering in CMF
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16: Henning Schliephake
Challenges in the use of cell-based devices and growth factors in
bone repair
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17: Paul H Krebsbach
Combinational therapy in craniofacial regeneration
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18: Jens Kuschnierz
Hard tissue regeneration in the maxillary sinus using methods of
tissue engineering
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19: Lim Kwong Cheung
Tissue engineering for mandibular bone lengthening in smokers
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20 : Franz E Weber
Small chemicals to enhance bone repair
Tissue and Bio-engineering in SPINE
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21: Stephen Ferguson
AOSpine Research Network: Global collaboration to address disc degeneration
and regeneration
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22: Fackson Mwale
Novel polymers for studies in stem cell differentiation and nucleus
pulposus supplementation
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23: Francis C Chan and J Hu Y Cheng
Enhanced spinal fusion by tissue engineering of mesenchymal stem
cell / Tricalcium phosphate ceramics composite - an experimental
study with non-decorticated posterior spinal fusion
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24: Dimitris Kletsas
Stress and homeostasis in bone and the intervertebral disc
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25: James C Iatridis
Intervertebral disc mechanobiology and the kinetics of gene expression
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26: Adrian Sugar
Clinical needs and applications of biotechnology in CMF
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27: Pierre-Yves Zambelli
From basic research to clinical application
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28: Allen Goodship
Fracture healing and its potential as a bioreactor for skeletal
tissue engineering
Cell Based Therapy I
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29: Georg N Duda
The role of periosteal cells and mesenchymal stem cells in the physiological
healing process of long- bone defects. Potential regeneration acceleration
by autologous cell transplantation
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30 : Luis Filgueira
Processing of metals by human bone and immune cells
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31: Dominique P Pioletti
Treatment of non-union fracture with fetal cells therapy
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32: Philip Kasten
Bone regeneration with platelet-rich plasma, calcium phosphate ceramics,
and stem cells
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33: Teppo Jarvinen
Estrogen-withdrawal increases the mechanosensitivity of bones to
loading
Cell Based Therapy II
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34: Keita Ito
Mechanoregulation of cell phenotype for musculoskeletal tissue engineering
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35: Philipp Niemeyer
HLA-independent transplantation of human mesenchymal stem cells
from bone marrow and adipose tissue for regeneration of bone
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36: Ivan Martin
Bioreactor-based engineering of osteoinductive grafts
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37: José Toro
PTH and alendronate improve osteotomy healing in an osteoporotic
rat model
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38: Mauro Alini
An engineered vascularized graft for large bone defects
Special Session
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39: David Winkler
Swiss MD-PhD Association (SMPA): a way to bridge the gap between
the bench and the patient's bed
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40: Adrian Sugar and Margarethe Hofmann-Amtenbrink
Biotechnology funding in the AO Foundation
Tissue Engineering & Gene Therapy
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41: Catherine El-Bez
Ethical considerations
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42: Jeffrey Hubbell
Nonviral DNA vectors in bone regeneration
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43: Zachary Abramson
PDGF gene therapy to promote oral implant osseointegration
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44: Anthony Freemont
Gene therapy in regeneration of the intervertebral disc
Biomedical Engineering
Page 45: Olivier Michielin
Molecular modelling of proteins: from simulations to patients NO
ABSTRACT
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46: Yuelian Liu
Bone formation enhancement by BMP-2-functionalized implant coatings
-a study in miniature pigs
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47: Clemens Franz
Characterizing cell adhesion and migration on surfaces biofunctionalized
with nanopatterned collagen matrices
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48: Ling Qin
Quantification of porosity, connectivity, and material density of
calcium phosphate ceramic implants using micro-computed tomography
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49: Helen E Gruber
Optimization of extracellular matrix production and gene expression
by human annulus cells in three-dimensional constructs
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50: Tero Järvinen
Targeted delivery of natural TGF-ß antagonist suppresses scar
formation during wound healing
Technical Poster Presentations
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51: C Seebach, D Henrich, A Scherzed, M Alini, I Marzi
"Early" endothelial progenitor cells (EPC) on ß-Tricalcium
Phosphate scaffold under osteogenic conditions are useful for vascularisation
in bone tissue engineering
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52: FCW Chan, K Lee, L Qin, K Leung, JCY Cheng
Enhanced bone formation by low intensity pulsed ultrasound in posterior
spinal fusion with Hydroxyapatite/ Tricalcium Phosphate implant
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53: FCW Chan, K Wong, K Lee, L Qin, H Fan, YY Hu, JCY Cheng
Mesenchymal stem cells pre-exposed to Basic Fibroblast Growth Factor
did not enhance additional bone formation in posterior spinal fusion
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54: LW Zheng, L Ma, LK Cheung
Effect of nicotine on mandibular distraction osteogenesis: a radiological
and immunohistochemical study
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55: CE Evans, F Li, S Khan, J-H Kuiper
A study of the activity of patients treated with Ilizarov Fixator
using the Physical Activity Monitor (PAM)
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56: J Toro, K Voellmicke, A Tomin, B Shore, L Spevak, A Boskey,
JM Lane
Characterisation of the osteotomy callus using FT-IRI in a rabbit
ulnar model
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57: S Sauerbier, G Lauer, N Weyer, J Kuschnierz, N Liebehenschel,
R Schön, R Schmelzeisen, R Gutwald
Synopsis of soft tissue engineering methods in reconstructive oral
and maxillofacial surgery
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58: S Sauerbier, P Voss, N Weyer, J Kuschnierz, C Zizelmann,
R Schön,R Gutwald, R Schmelzeisen
Sinus augmentation with periosteum derived tissue engineered bone
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59: M Hinze, S Sauerbier, M Wiedmann-Al-Ahmad, U Hübner,
R Schmelzeisen, R Gutwald
Bone engineering: allogenic and alloplastic bone transplants vitalized
by Osteoblast-like cells
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60: JM Mesa, CR Nuttelman, KS Anseth, MJ Yaremchuk, MA Randolph
Effect of 3D hydrogel scaffolds on the chondrodifferentiation of
swine mesenchymal stem cells in vivo
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61: TJ Gill, C Weinand, GM Peretti, SB Adams, MA Randolph
Cellular repair of meniscal tears in the avascular region
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62: I Gerber, H Gerber, T Wallimann
Creatine, pyruvate and glucose influence viability, metabolic activity
and collagen content of normal and osteoporotic human osteoblast-like
cells in vitro
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63: D Winkler, L Otten, L Jeker, D Andel, S Viatte
The Swiss MD-PhD association (SMPA): a way to bridge the gap between
the bench and the patient's bed
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64: LT Jeker, T Barthlott, S Zuklys, MP Keller, GA Holländer
Thymic epithelial cell-specific smad4 deficiency leads to lymphopenia
and an increased suppressive capacity of CD103+CD25+CD4+ T cells
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65: S Viatte, PM Alves, C Servis, N Lévy, G Theiler,
D Rimoldi, VC Jongeneel, J-C Cerottini, F Lévy, P Romero
An optimized T cell epitope forecast approach for the identification
of new human antigenic peptides derived from tumor-expressed splice
variants
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66: S Kall, K Reimers, CYU Choi, ER Garcia, PM Vogt
Long tendon constructs can be fabricated from rabbit adipose derived
stem cells (rADSCs) and a collagen type I gel by cyclic stretching
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67: JS Hayes, CW Archer, RG Richards
Controlling hard tissue integration at the bone-implant interface
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68: AE Simpson, MJ Stoddart , PI Furlong, CM Davies, DB Jones,
RG Richards
Mechanically loaded ex vivo culture system for cancellous
bone biopsies
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69: MJ Stoddart, PI Furlong, AE Simpson, CM Davies, RG Richards
Viability in ex vivo cultured cancellous bone
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70: RR. Maddikeri, S Tosatti, M. Textor, R.G. Richards, LG Harris
Bacterial adhesion to PLL-g-PEG modified surfaces
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71: AT Mehlhorn, K Utchiyama, H Schmal, P Niemeyer, A Petri-Fink,
H Hofmann, NP Südkamp
Super-paramagnetic nanoparticles for enhancement of bone growth
and differentiation
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72: H Hofmann, B Steitz, A Petri-Fink
Nanotechnology in Medicine: Nanoparticles/structures for drug and
gene delivery and hyperthermia
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73: K Dittmar, H Hofmann, A Tourvieille, L-D Piveteau
Nanostructured Smart Drug Delivery Coatings
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74: A Quintin, C Scakletta, S Jaccoud, D Pioletti, C Schizas,
L-A Appelgate
Fetal spine cells for intervertebral disc regeneration: preliminary
characterization
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75: AI Pearce, SG Pearce, S Milz, CW Archer, RG Richards
In vivo evaluation of cpTi and TAN screws with modified surfaces
to reduce bony integration
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76: SZ Sharifullina, NI Chupikova, VS Yeremenko, NY Vasyunina,
SV Korzhikova, AS Teplyashin
Perspective of clinical application of human MSC cells after laser
dermabrasion
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77: DO Meredith, LG Harris, MO Riehle, ASG Curtis, RG Richards
Effect of metal implant surface topography on fibroblast behaviour
and bacterial adhesion
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78: MJ Stoddart, AE Simpson, PI Furlong, CM Davies, DB Jones,
J Gasser, BS Noble, CW Archer, RG Richards
Mechanically loaded ex vivo culture system for cancellous
bone biopsies
Page 79: R Meier
CXCR4 differentially enhances aggressive behaviour of neuroblastoma
NO ABSTRACT
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