Alginate hydrogel-guided rAAV-mediated FGF-2 and TGF-β delivery and overexpression stimulates the biological activities of human meniscal fibrochondrocytes for meniscus repair
J.K.Venkatesan 1, W.Liu 1, H.Madry 1,2, M.Cucchiarini 1,*
Affiliations
Article Info
1 Center of Experimental Orthopaedics, Saarland University Medical Center and Saarland University, 66421 Homburg, Saar, Germany
2 Department of Orthopaedic Surgery, Saarland University Medical Center and Saarland University, 66421 Homburg, Saar, Germany
Graphical Abstract
Keywords
- Human meniscal fibrochondrocytes
- recombinant adeno-associated virus
- fibroblast growth factor 2
- transforming growth factor beta
- alginate hydrogel
- reparative activities