eCM (Eur Cell Mater / e Cells & Materials) Not-for-Profit Open Access
Created by Scientists, for Scientists
 ISSN:1473-2262         NLM:100973416 (link)         DOI:10.22203/eCM

C2007   Volume No 13 – pages 76-86

Title: Quantitative magnetic resonance imaging of articular cartilage in osteoarthritis

Author: G Blumenkrantz, S Majumdar

Address: Department of Radiology, University of California San Francisco, San Francisco, CA

E-mail: sharmila.majumdar at

Key Words: Magnetic resonance imaging, osteoarthritis, cartilage, collagen, proteoglycan.

Publication date: May 15th 2007

Abstract: Magnetic resonance imaging of articular cartilage has recently been recognized as a tool for the characterization of cartilage morphology, biochemistry and function. In this paper advancements in cartilage imaging, computation of cartilage volume and thickness, and measurement of relaxation times (T2 and T1Ρ) are presented. In addition, the delayed uptake of Gadolinium DTPA as a marker of proteoglycan depletion is also reviewed. The cross-sectional and longitudinal studies using these imaging techniques show promise for cartilage assessment and for the study of osteoarthritis.

Article download: Pages 76-86 (PDF file)
DOI: 10.22203/eCM.v013a08